Module 14 · Anaesthesia Blueprints
Prepare neuroanaesthesia for postgraduate anaesthesia examinations with structured notes, exam-style questions and referenced explanations from standard textbooks and current guidelines.
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Q1. During spine surgery with intra-operative neuromonitoring, which modality is MOST sensitive to suppression by volatile anaesthetics?
Answer D: Transcranial motor evoked potentials
Transcranial MEPs depend on multiple synapses (cortex, anterior horn cell) and are the most sensitive to volatile agents; monitorability degrades non-linearly over a narrow dose range. TIVA (propofol + remifentanil) without neuromuscular blockade is preferred when MEPs are monitored.
Exam style: NEET-SS Anaesthesia
Q2. The MOST sensitive monitor for detecting venous air embolism during sitting craniotomy is:
Answer C: Transoesophageal echocardiography
TOE detects as little as 0.02 mL/kg of air and can also identify paradoxical air crossing a PFO. Precordial Doppler is the most sensitive non-invasive monitor; EtCO₂ falls (and EtN₂ rises) with clinically significant embolism.
Exam style: NEET-SS Anaesthesia
Q3. Normal global cerebral blood flow in an adult is approximately:
Answer C: 50 mL/100 g/min
Global CBF ≈ 50 mL/100 g/min (≈ 750 mL/min, ~15% of cardiac output) — grey matter ≈ 80 mL/100 g/min, white matter ≈ 20. EEG slowing appears below ≈ 20–25 mL/100 g/min and membrane failure/infarction below ≈ 10–15.
Exam style: NEET-SS Anaesthesia
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